Single-cell RNA sequencing reveals the heterogeneity and microenvironment of temporal bone squamous cell carcinoma

This study is the first to unveil the complex heterogeneity and tumor microenvironment characteristics of TBSCC using scRNA-seq technology, offering new avenues for diagnosing, classifying, and treating this rare carcinoma.

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Publication Details

Journal
Clinical and Experimental Otorhinolaryngology
Published
2026-02-05
DOI
https://doi.org/10.21053/ceo.2025-00324
Primary Topic
Single-cell and spatial transcriptomics
Type
article
Field-Weighted Citation Impact
0.00
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article

Single-cell RNA sequencing reveals the heterogeneity and microenvironment of temporal bone squamous cell carcinoma

Chuan Xu, Binhong Liao, Linfei Mao, Tianjiao Zhou et al.
Clinical and Experimental Otorhinolaryngology
Single-cell and spatial transcriptomics
article

Single-cell RNA sequencing reveals the heterogeneity and microenvironment of temporal bone squamous cell carcinoma

Chuan Xu, Binhong Liao, Linfei Mao, Tianjiao Zhou, haibo shi, Z L Li, Jin Li, Lu Wen, Yini Li, D Z Yu, Zhengnong Chen
article en

Abstract

This study is the first to unveil the complex heterogeneity and tumor microenvironment characteristics of TBSCC using scRNA-seq technology, offering new avenues for diagnosing, classifying, and treating this rare carcinoma.

Clinical and Experimental Otorhinolaryngology
Sun Yat-sen University (CN), Shanghai Jiao Tong University (CN), Sun Yat-sen Memorial Hospital (CN), Ministry of Education (KR), Shanghai Sixth People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 66%
Single-cell and spatial transcriptomics
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Single-cell RNA sequencing reveals the heterogeneity and microenvironment of temporal bone squamous cell carcinoma — Chuan Xu, Binhong Liao, et al. · Clinical and Experimental Otorhinolaryngology (2026) | TGRS Research Map | TGRS