CXCL11 levels regulate lung Treg responses to deter the onset of HIV-related COPD
These findings indicate that cigarette smoke activates c-Src to suppress CXCL11 levels thereby diminishing lung Treg responses that counter airways disease and lung tissue destruction in HIV-infected individuals.
Authors
- Patrick Geraghty (ORCID: https://orcid.org/0000-0003-1647-5505)
- Abdoulaye Dabo
- David J. Volsky (ORCID: https://orcid.org/0000-0001-6788-1752)
- Boe-Hyun Kim
- Mary Jane Potash (ORCID: https://orcid.org/0000-0002-4640-8269)
- Oleg V. Evgrafov (ORCID: https://orcid.org/0000-0003-0167-3939)
- Michael Campos (ORCID: https://orcid.org/0000-0001-5485-9062)
- Eran Hadas (ORCID: https://orcid.org/0000-0001-7966-8326)
- Robert F. Foronjy
Institutions
- State University of New York (US)
- University of Miami (US)
- SUNY Downstate Health Sciences University (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Respiratory Research
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1186/s12931-026-03495-8
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00