The Role of PDE3A in Cancer
PDE3A plays a pivotal role in tumorigenesis and cancer progression, with aberrant expression strongly associated with tumor proliferation, metastasis, and resistance to chemotherapy. As a therapeutic target, PDE3A holds significant potential. The development of PDE3A inhibitors or molecular adhesive agents may offer novel treatment strategies, particularly for chemotherapy-resistant tumor types.
Authors
- Qihe Zhang
- Bohong Chen (ORCID: https://orcid.org/0000-0003-2745-1015)
- Jingyi Lei
- Shengyu Pu
- Na Hao
- Mi Miao
- Jiarui Xu
- Xiaojiang Tang
Institutions
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- ACS Omega
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1021/acsomega.5c10194
- Primary Topic
- Phosphodiesterase function and regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00