Differential effects of preoperative cholangitis and biliary stenting in long-term survival of patients undergoing surgery for perihilar cholangiocarcinoma
Preoperative cholangitis, particularly when combined with biliary stenting, is associated with significantly worse perioperative outcomes and long-term survival in patients with perihilar cholangiocarcinoma. These results underscore the importance of prophylactic antibiotics in the preoperative phase and call for strategies aimed at reducing stent-associated cholangitis.
Authors
- Sauer Igor
- Thomas Malinka (ORCID: https://orcid.org/0000-0002-5860-5710)
- J. Pratschke
- Eriselda Keshi (ORCID: https://orcid.org/0000-0002-1780-9151)
- Sebastian Knitter (ORCID: https://orcid.org/0000-0001-9232-6793)
- Wenzel Schöning (ORCID: https://orcid.org/0000-0002-0446-5126)
- Nathanael Raschzok (ORCID: https://orcid.org/0000-0001-5074-7063)
- Karl H. Hillebrandt (ORCID: https://orcid.org/0000-0002-5114-6590)
- Florian Siemund (ORCID: https://orcid.org/0009-0006-5506-8741)
- Nils Haep
- Philipp Haber
Institutions
- Humboldt-Universität zu Berlin (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- European Journal of Surgical Oncology
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1016/j.ejso.2026.111448
- Primary Topic
- Gallbladder and Bile Duct Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00