Photocatalytic Synthesis of (Hetero)biaryls via Palladium-Catalyzed Hybrid-Radical Cross-Coupling of (Hetero)aryl Halides and C–H Functionalization of Heteroarenes
Light activates palladium catalysts to enable radical C-H (hetero)-arylation of heterocycles using simple (hetero)-aryl halides. Without the need of an external photocatalyst, the reaction proceeds under mild conditions with broad functional-group tolerance and high site selectivity, expanding photoactivated palladium catalysis for sustainable C-C bond formation in complex bi-(hetero)-aryl scaffolds.
Authors
- Claudia Poehner
- René M. Koenigs (ORCID: https://orcid.org/0000-0003-0247-4384)
- Claire Empel (ORCID: https://orcid.org/0000-0002-9362-7755)
- Sandip Murarka (ORCID: https://orcid.org/0000-0003-1692-0939)
- Lennard Kloene (ORCID: https://orcid.org/0000-0002-9587-9219)
- Sneha Chandra
- Sudip Senapati
Institutions
- Indian Institute of Technology Jodhpur (IN)
- University of Bayreuth (DE)
- Martin Luther University Halle-Wittenberg (DE)
- RWTH Aachen University (DE)
Publication Details
- Journal
- JACS Au
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1021/jacsau.5c01634
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00