E-cigarette Duration and Incident COPD Among Adults Aged 40 Years and Older with a Smoking History

Prolonged e-cigarette use may increase COPD risk among individuals with pre-existing respiratory vulnerabilities. Although switching from combustible cigarettes remains an important harm reduction strategy, behavioral counseling and pharmacotherapy should be prioritized for those at high risk for COPD, with e-cigarette cessation support available to high-risk former smokers. Continued surveillance and research are warranted as e-cigarette products and use patterns evolve.

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Publication Details

Journal
medRxiv
Published
2026-02-05
DOI
https://doi.org/10.64898/2026.02.04.26345592
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
Field-Weighted Citation Impact
0.00

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article

E-cigarette Duration and Incident COPD Among Adults Aged 40 Years and Older with a Smoking History

Andrew F. Brouwer, Nancy L. Fleischer, Rafael Meza, Steven Cook et al.
medRxiv
Chronic Obstructive Pulmonary Disease (COPD) Research
article

E-cigarette Duration and Incident COPD Among Adults Aged 40 Years and Older with a Smoking History

Andrew F. Brouwer, Nancy L. Fleischer, Rafael Meza, Steven Cook, Kenneth M Cummings, Doug A Arenberg
article en

Abstract

Prolonged e-cigarette use may increase COPD risk among individuals with pre-existing respiratory vulnerabilities. Although switching from combustible cigarettes remains an important harm reduction strategy, behavioral counseling and pharmacotherapy should be prioritized for those at high risk for COPD, with e-cigarette cessation support available to high-risk former smokers. Continued surveillance and research are warranted as e-cigarette products and use patterns evolve.

medRxiv
Rutgers, The State University of New Jersey (US), University of British Columbia (CA), Medical University of South Carolina (US), University of Michigan (US), Institute of Population and Public Health (CA)
National Institutes of Health, National Cancer Institute, Center for Tobacco Products
Good health and well-being
Openalex Percentile: Top 67%
Chronic Obstructive Pulmonary Disease (COPD) Research
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E-cigarette Duration and Incident COPD Among Adults Aged 40 Years and Older with a Smoking History — Andrew F. Brouwer, Nancy L. Fleischer, et al. · medRxiv (2026) | TGRS Research Map | TGRS