Assessing the accuracy of 3D assistive technologies for surgical guidance of osteosarcoma resections: a comparative laboratory study of mixed reality, patient-specific instruments and freehand approaches

This study acts as a non-clinical proof of concept that the adoption of patient-specific instrumentation or mixed reality techniques for osteosarcoma resection might enable narrower margins pending in-vivo validation, potentially enabling bone and joint preservation and restoration, while decreasing resection failure rates.