Mullerianosis of the Urinary Bladder: A Rare Case Report

Endocervicosis, endometriosis, and endosalpingosis are choristomas derived from Müllerian tissue, collectively termed Müllerianosis. We report a 40-year-old woman with pelvic pain and dysuria who presented with a 3.2×2.5 cm bladder mass four years post-hysterectomy. Transurethral resection revealed endocervical glands and endometrial stroma deep in the bladder wall. Immunohistochemistry confirmed ER/PR positivity in glandular epithelium and CD10 positivity in stroma, establishing the diagnosis of Müllerianosis. Outcome: The patient remained asymptomatic with no recurrence over 8 years of clinical and cystoscopic follow-up. Müllerianosis is a rare benign bladder lesion that can mimic malignancy. Accurate histopathological diagnosis with immunohistochemistry is essential to avoid unnecessary radical surgery and enable hormonal therapy when indicated.