Continuous outcome estimation in N‐of‐1 trials for accelerated decision‐making
Treatment efficacy decisions can be expedited when outcome estimation is performed continuously rather than delayed until the end of the trial. Clinical significance of N-of-1 trial outcome can be improved combining both Bayesian hypothesis testing and a minimally clinically important threshold.
Authors
- Victoria Defelippe (ORCID: https://orcid.org/0000-0002-3080-5008)
- Frantis̆ek Bartos̆ (ORCID: https://orcid.org/0000-0002-0018-5573)
- Eric‐Jan Wagenmakers (ORCID: https://orcid.org/0000-0003-1596-1034)
- F.M. Jansen
- Willem M. Otte
- Kees P. J. Braun
Institutions
- Utrecht University (NL)
- University Medical Center Utrecht (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Epilepsia
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1002/epi.70119
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Health~Holland