Cutaneous Perineurioma of the Medial Superciliary Arch: An Uncommon Location for a Rare, Benign Spindle Cell Neoplasm

Cutaneous perineuriomas are rare, benign peripheral nerve sheath tumors that are often mistaken for other adnexal or spindle cell lesions, with facial involvement being uncommon. Recognition is important to ensure accurate diagnosis and avoid unnecessary overtreatment. We report a case of a 36-year-old Hispanic woman with a slowly enlarging papule of the left medial superciliary arch, histologically and immunophenotypically confirmed as a cutaneous perineurioma. This case highlights the clinicopathologic features, immunohistochemical profile, and management considerations of cutaneous perineurioma arising in a rare, cosmetically sensitive facial location, adding to the limited body of published cases.

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Publication Details

Journal
Cureus
Published
2026-02-05
DOI
https://doi.org/10.7759/cureus.103023
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
Field-Weighted Citation Impact
0.00
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article

Cutaneous Perineurioma of the Medial Superciliary Arch: An Uncommon Location for a Rare, Benign Spindle Cell Neoplasm

Kara Asbury, Sri Naidnur, Emily DeSantis, Rick Lin et al.
Cureus
Neurofibromatosis and Schwannoma Cases
article

Cutaneous Perineurioma of the Medial Superciliary Arch: An Uncommon Location for a Rare, Benign Spindle Cell Neoplasm

Kara Asbury, Sri Naidnur, Emily DeSantis, Rick Lin, Valeria González-Molina
article en

Abstract

Cutaneous perineuriomas are rare, benign peripheral nerve sheath tumors that are often mistaken for other adnexal or spindle cell lesions, with facial involvement being uncommon. Recognition is important to ensure accurate diagnosis and avoid unnecessary overtreatment. We report a case of a 36-year-old Hispanic woman with a slowly enlarging papule of the left medial superciliary arch, histologically and immunophenotypically confirmed as a cutaneous perineurioma. This case highlights the clinicopathologic features, immunohistochemical profile, and management considerations of cutaneous perineurioma arising in a rare, cosmetically sensitive facial location, adding to the limited body of published cases.

CureusVol. 18(2)
Bay Area Medical Center (US), OASIS Clinic (US), CS Diagnostics (DE)
Gender equality
Openalex Percentile: Top 67%
Neurofibromatosis and Schwannoma Cases
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