Postsurgical perilesional functional connectivity predicts neurological outcome in glioma patients
Overall, our study showed that resting-state fMRI from patients after glioma resection is relevant to their long-term neurological outcomes: decreased connectivity in the perilesional regions compared to the contralateral regions indicates less survival time and worsened functional outcomes. The reported analytics from postsurgical fMRI scans, combined with the machine learning model, could provide important prognostic information for postsurgical recovery management.
Authors
- Tressie M. Stephens
- Alissa Schroeder
- Ian F. Dunn
- Lei Ding
- Derek Madden
- Mingwei Huang
- Han Yuan
Institutions
- Stephens College (US)
- Institute for Biomedical Engineering (CH)
- University of Oklahoma Health Sciences Center (US)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2026-02-05
- DOI
- https://doi.org/10.3389/fnins.2026.1751746
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Oklahoma
- National Institutes of Health
- University of Oklahoma Health Sciences Center
- National Institute of General Medical Sciences