Clonal cacophony of AML relapse

In this issue of Blood, Turkalj et al 1 demonstrate using single-cell sequencing that rapid emergence of acute myeloid leukemia clones within 1 to 3 months of ivosidenib combination therapy foreshadows overt clinical relapse years later.

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Publication Details

Journal
Blood
Published
2026-02-05
DOI
https://doi.org/10.1182/blood.2025032092
Primary Topic
Retinoids in leukemia and cellular processes
Type
article
Field-Weighted Citation Impact
0.00
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article

Clonal cacophony of AML relapse

Eunice S. Wang
Blood
Retinoids in leukemia and cellular processes
article

Clonal cacophony of AML relapse

Eunice S. Wang
article en

Abstract

In this issue of Blood, Turkalj et al 1 demonstrate using single-cell sequencing that rapid emergence of acute myeloid leukemia clones within 1 to 3 months of ivosidenib combination therapy foreshadows overt clinical relapse years later.

BloodVol. 147(6)
Roswell Park Comprehensive Cancer Center (US)
Zero hunger
Openalex Percentile: Top 66%
Retinoids in leukemia and cellular processes
DOIOpen Access PDFOpenAlex
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Clonal cacophony of AML relapse — Eunice S. Wang · Blood (2026) | TGRS Research Map | TGRS