Blinatumomab Nonresponse Correlates with Poor Survival After Brexucabtagene
In a real-world analysis of brexucabtagene autoleucel (brexu-cel) recipients with relapsed/refractory B-ALL (n = 278), lack of response to prior blinatumomab correlates with significantly worse post CAR-T outcomes.
Authors
- Jozal Moore (ORCID: https://orcid.org/0000-0003-4811-5790)
- Rawan Faramand (ORCID: https://orcid.org/0000-0001-7750-781X)
- Joshua Sasine (ORCID: https://orcid.org/0000-0001-9866-462X)
- Christian Gordillo (ORCID: https://orcid.org/0000-0003-4829-1954)
- Fevzi Yalniz (ORCID: https://orcid.org/0000-0003-3569-8632)
- George Yaghmour (ORCID: https://orcid.org/0000-0002-6988-3556)
- Navneet S. Majhail (ORCID: https://orcid.org/0000-0001-7082-891X)
- Marlise Rachael Luskin (ORCID: https://orcid.org/0000-0002-5781-4529)
- TIMOTHY E. O'CONNOR
- Roshini Pradeep
- Omer Jamy (ORCID: https://orcid.org/0000-0003-2411-4742)
- Stephen A. Strickland (ORCID: https://orcid.org/0000-0002-6861-2041)
- Caspian Oliai (ORCID: https://orcid.org/0000-0002-6368-8557)
- Jessica Leonard (ORCID: https://orcid.org/0000-0001-5576-0048)
- Tamer Adel Othman (ORCID: https://orcid.org/0000-0001-6376-4495)
- Vivian Irizarry Gatell (ORCID: https://orcid.org/0000-0001-6436-9999)
- Eunice S. Wang (ORCID: https://orcid.org/0000-0002-8644-0968)
- C F Lee
- Olalekan O. Oluwole (ORCID: https://orcid.org/0000-0001-8525-9641)
- Gregory W. Roloff (ORCID: https://orcid.org/0000-0003-2109-5152)
- Razan Mohty (ORCID: https://orcid.org/0000-0002-0189-8233)
- Noam E. Kopmar (ORCID: https://orcid.org/0000-0001-8710-9217)
- B. D. Shah
- Muthu Sendhil Kumaran (ORCID: https://orcid.org/0000-0002-8091-101X)
- Caitlin Guzowski
- Karamjeet Sandhu (ORCID: https://orcid.org/0000-0001-8024-8484)
- M. Ulrickson
- Ryan D. Cassaday (ORCID: https://orcid.org/0000-0002-3424-2425)
- Sean Tracy (ORCID: https://orcid.org/0000-0001-7047-2589)
- Miller Kk
- Kaitlyn C. Dykes (ORCID: https://orcid.org/0000-0002-1638-1755)
- Anjali S. Advani (ORCID: https://orcid.org/0000-0003-0015-5902)
- Hrishikesh K. Srinagesh (ORCID: https://orcid.org/0000-0001-9786-3010)
- Yannis K. Valtis (ORCID: https://orcid.org/0000-0001-8927-8006)
- Michael Daunov (ORCID: https://orcid.org/0000-0002-3641-6265)
- Virginia Tan
- Ross McCauley (ORCID: https://orcid.org/0000-0002-8499-1782)
- Vishal Gupta (ORCID: https://orcid.org/0000-0003-3574-1805)
- L Hill
- Katherine C. Sutherland (ORCID: https://orcid.org/0009-0006-5935-8279)
- Aaron Logan
- Jacob Boccucci
- Lori Muffly
- Talal Hilal
- Chenyu Lin
- Melhem M Solh
- Vamsi Kota
- Kristen M O'Dwyer
- Rasmus T. Hoeg
- Kevin Tang
- Ibrahim Aldoss
- Stephanie B. Tsai
- Veronika Bachanova
- Evan C. Chen
- Amy Zhang
- Clayton Jackson
- Matthew P Connor
- Jae H Park
- Michael R Grunwald
- Bhagirathbhai Dholaria
- Marc S. Schwartz
- Kenneth Byrd
- Wendy A Stock
- Silvina Odstrcil Bobillo
- Sumithira Vasu
Institutions
- Northside Hospital (US)
- University of Southern California (US)
- Cedars-Sinai Medical Center (US)
- Roswell Park Comprehensive Cancer Center (US)
- City Of Hope National Medical Center (US)
- Loyola University Medical Center (US)
- Cleveland Clinic (US)
- Memorial Sloan Kettering Cancer Center (US)
- University of Kentucky (US)
- University of Kansas (US)
- University of California, Los Angeles (US)
- Oregon Health & Science University (US)
- Duke University (US)
- Palo Alto University (US)
- University of California, San Francisco (US)
- Baylor College of Medicine (US)
- University of Washington (US)
- University of Utah (US)
- University Hospitals of Cleveland (US)
- Columbia University Irving Medical Center (US)
- University of Arkansas Medical Center (US)
- UCLA Health (US)
- Hospital of the University of Pennsylvania (US)
- University of Minnesota System (US)
- Huntsman Cancer Institute (US)
- University of Rochester Medical Center (US)
- Moffitt Cancer Center (US)
- University of Alabama at Birmingham (US)
- University of California San Diego (US)
- University of Chicago (US)
- Augusta University Health (US)
- Centennial Medical Center (US)
- Fred Hutch Cancer Center (US)
- Southwestern Medical Center (US)
- Levine Cancer Institute (US)
- Children’s Hospital at TriStar Centennial (US)
- Sarah Cannon (US)
- City of Hope (US)
- HOPE Clinic (US)
- Dana-Farber Cancer Institute (US)
- Mayo Clinic Hospital (US)
- Banner MD Anderson Cancer Center
- University of Colorado Anschutz Medical Campus (US)
- The Ohio State University (US)
- University of Rochester (US)
- University of Pennsylvania (US)
- University of California, Davis (US)
- The University of Texas Southwestern Medical Center (US)
- Vanderbilt University Medical Center (US)
- Stanford University (US)
Publication Details
- Journal
- Blood
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1182/blood.2025031734
- Citations
- 1
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 24.20