Pediatric Sarcomas With BCOR and CIC Aberrations: Advanced Diagnosis and Treatment Outcomes

Despite the relatively favorable outcomes in BCOR sarcomas, the relapse rate is considerable, whereas pediatric patients with CIC sarcoma typically develop metastatic disease and have poor outcomes. The data provide a prospective foundation for genetically based therapeutic strategies and risk stratification.

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Publication Details

Journal
Archives of Pathology & Laboratory Medicine
Published
2026-02-05
DOI
https://doi.org/10.5858/arpa.2025-0055-oa
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Pediatric Sarcomas With BCOR and CIC Aberrations: Advanced Diagnosis and Treatment Outcomes

Николай Сергеевич Грачев, А. Е. Druy, Ksenia Sinichenkova, N. Usman et al.
Archives of Pathology & Laboratory Medicine
Sarcoma Diagnosis and Treatment
article

Pediatric Sarcomas With BCOR and CIC Aberrations: Advanced Diagnosis and Treatment Outcomes

Николай Сергеевич Грачев, А. Е. Druy, Ksenia Sinichenkova, N. Usman, Alexander Karachunskiy, Ruslan Kh. Abasov, Ilya V Sidorov, Dmitry Litvinov, Agnesa Panferova, Alexey Chernev
article en

Abstract

Despite the relatively favorable outcomes in BCOR sarcomas, the relapse rate is considerable, whereas pediatric patients with CIC sarcoma typically develop metastatic disease and have poor outcomes. The data provide a prospective foundation for genetically based therapeutic strategies and risk stratification.

Archives of Pathology & Laboratory Medicine
Saint-Petersburg Medico-Social Institute (RU), Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology (RU)
No poverty
Openalex Percentile: Top 67%
Sarcoma Diagnosis and Treatment
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