Trends in the Hidden Burden of Cancer in an Autopsy-Based Study Over 66 Years in Japan
This cohort study of autopsies across Japan found a substantial reservoir of undiagnosed cancer, including some with metastatic potential. These findings highlight the persistent value of autopsy for assessing cancer burden and underscore the need to refine approaches for early detection while minimizing overdiagnosis.
Authors
- Maiko Tsuchiya (ORCID: https://orcid.org/0009-0001-1747-8102)
- Yoshinao Kikuchi (ORCID: https://orcid.org/0000-0001-6430-7560)
- Shiori Watabe
- Masahiro Kato (ORCID: https://orcid.org/0000-0003-0612-703X)
- Masato Watanabe (ORCID: https://orcid.org/0000-0001-9442-2762)
- Mariko Yasui
- Hiroshi Uozaki (ORCID: https://orcid.org/0000-0002-4721-8467)
Institutions
- Teikyo University (JP)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.57812
- Primary Topic
- Autopsy Techniques and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00