Effects of Dietary Weight Loss on Brain-Derived Neurotrophic Factor in Individuals With Overweight and Obesity: A Systematic Review
These findings suggest that diet-induced weight loss can influence neurotrophic status, potentially modulating brain health. However, results are inconsistent across studies. Overall, interventions involving intermittent calorie restriction, MIND, and/or KD, more frequently reported BDNF increases, whereas continuous calorie restriction produced mixed results.
Authors
- Arezoo Salarpour
- Arvin Porkar rezaeyeh
- Leila Hajizadeh
- Damoon Ashtary‐Larky (ORCID: https://orcid.org/0000-0001-7968-6110)
- Meysam Alipour (ORCID: https://orcid.org/0000-0003-3722-0528)
- Zahra Shouhani
Institutions
- Ahvaz Jundishapur University of Medical Sciences (IR)
- Razi Vaccine and Serum Research Institute (IR)
- Iran University of Medical Sciences (IR)
- Islamic Azad University, Marvdasht (IR)
- Islamic Azad University, Shoushtar Branch (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Nutrition Reviews
- Published
- 2025-12-23
- DOI
- https://doi.org/10.1093/nutrit/nuaf308
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 0.00