Localized low muscle mass is associated with hand dysfunction beyond inflammation in rheumatoid arthritis: a cross-sectional study

The present cross-sectional study demonstrates that localized low muscle mass of the upper extremities is associated with hand dysfunction in RA, independent of inflammation. These findings support the need for further longitudinal studies to explore the potential benefits of incorporating routine muscle assessments into RA care.

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Publication Details

Journal
PeerJ
Published
2026-02-06
DOI
https://doi.org/10.7717/peerj.20629
Primary Topic
Rheumatoid Arthritis Research and Therapies
Type
article
Field-Weighted Citation Impact
0.00
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article

Localized low muscle mass is associated with hand dysfunction beyond inflammation in rheumatoid arthritis: a cross-sectional study

Lie Dai, Yuting Fan, Yao-Wei Zou, Kui-Min Yang et al.
PeerJ
Rheumatoid Arthritis Research and Therapies
article

Localized low muscle mass is associated with hand dysfunction beyond inflammation in rheumatoid arthritis: a cross-sectional study

Lie Dai, Yuting Fan, Yao-Wei Zou, Kui-Min Yang, Jian-Da Ma, Pei-Wen Jia, Ye Lu, Tao Wu, Zhi-Ming Ouyang, Ran Shi, Jian-Zi Lin, Ya-Nan Cao, Ying Yang, PuiU Lam
article en

Abstract

The present cross-sectional study demonstrates that localized low muscle mass of the upper extremities is associated with hand dysfunction in RA, independent of inflammation. These findings support the need for further longitudinal studies to explore the potential benefits of incorporating routine muscle assessments into RA care.

PeerJVol. 14
Sun Yat-sen University (CN), Sun Yat-sen Memorial Hospital (CN)
Openalex Percentile: Top 67%
Rheumatoid Arthritis Research and Therapies
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