Generation and characterization of iPSC‐derived microglia for in vitro modeling of stimuli‐specific neuroimmune responses

We validated our iMG model system for the evaluation of biological responses of human microglia-like cells to stimuli and pharmacological agents for their transcriptional and functional impacts.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2026-02-01
DOI
https://doi.org/10.1002/alz.71117
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
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article

Generation and characterization of iPSC‐derived microglia for in vitro modeling of stimuli‐specific neuroimmune responses

Alan D. Palkowitz, Jacob Smiley, Alison Haskell, Louis F. Stancato et al.
Alzheimer s & Dementia
Neuroinflammation and Neurodegeneration Mechanisms
article

Generation and characterization of iPSC‐derived microglia for in vitro modeling of stimuli‐specific neuroimmune responses

Alan D. Palkowitz, Jacob Smiley, Alison Haskell, Louis F. Stancato, Rabea Hinkel, Joshua A. Kulas, Sylvia Robertson, Mustapha Moussaif, Abdul Qadir Syed, June Javens‐Wolfe, Shaoyou Chu, William Carter, Timothy I. Richardson, Olivia Lazaro, Jeffrey L. Dage, Bruce T. Lamb
article en

Abstract

We validated our iMG model system for the evaluation of biological responses of human microglia-like cells to stimuli and pharmacological agents for their transcriptional and functional impacts.

Alzheimer s & DementiaVol. 22(2)
Neurosciences Institute (US), Indiana Biosciences Research Institute (US), Indiana University School of Medicine, Indiana University – Purdue University Indianapolis (US)
Openalex Percentile: Top 71%
Neuroinflammation and Neurodegeneration Mechanisms
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Generation and characterization of iPSC‐derived microglia for in vitro modeling of stimuli‐specific neuroimmune responses — Alan D. Palkowitz, Jacob Smiley, et al. · Alzheimer s & Dementia (2026) | TGRS Research Map | TGRS