AIF-1 Drives Corneal Neovascularization by Promoting Inflammatory Macrophage Activation via the MAPK and PI3K/AKT/mTOR Signaling Pathways
AIF-1 played a pivotal role in CNV progression. AIF-1 promoted inflammatory macrophage activation, exacerbating corneal inflammation and neovascularization via the MAPK and PI3K/AKT/mTOR signaling pathways, which offers novel insights for CNV treatment.
Authors
- Hua Gao (ORCID: https://orcid.org/0009-0009-6431-8660)
- Xia Liu (ORCID: https://orcid.org/0000-0002-9209-0562)
- Qinghua Li
- Sihan Zhao
- Hui Yan
- Fan Wu
- Wenlong Li
- Qingdong Bao
- Yanshuo Xie
- Chaoqun Wei
Institutions
- Shandong Eye Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2026-02-06
- DOI
- https://doi.org/10.1167/iovs.67.2.22
- Citations
- 1
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 31.92