Summary of ceftriaxone-resistant <i>Neisseria gonorrhoeae</i> in Canada, 2017–24

We summarize 16 cases of ceftriaxone-resistant gonorrhoea that were isolated in Canada from 2017 to 2024. We determined the penA allele type for each case and detected molecular markers associated with cephalosporin resistance. Local public health investigations and the genomic data for each case indicate that the strains did not spread further in the population. To date, ceftriaxone remains an effective treatment for gonorrhoea, but continued surveillance is required to ensure detection and thus prevent the further spread of ceftriaxone-resistant Neisseria gonorrhoeae in Canada.