Triple Negative Breast Cancer With Choroidal Metastasis Responsive to Sacituzumab Govitecan and Radiation Therapy

This case report documents the first case of orbital metastases successfully treated with radiation therapy and sacituzumab govitecan. As such, this case highlights the importance of sacituzumab govitecan as a potentially effective option for TNBC patients with CNS disease. Further studies and real-world data are needed to investigate the efficacy of combined radiotherapy and sacituzumab govitecan toward ocular metastases.

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Publication Details

Journal
Cancer Reports
Published
2026-02-01
DOI
https://doi.org/10.1002/cnr2.70462
Primary Topic
Ocular Oncology and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Triple Negative Breast Cancer With Choroidal Metastasis Responsive to Sacituzumab Govitecan and Radiation Therapy

Nellie Nafissi, Nejina Rijal, Ritesh Parajuli, Aditya Mahadevan et al.
Cancer Reports
Ocular Oncology and Treatments
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Triple Negative Breast Cancer With Choroidal Metastasis Responsive to Sacituzumab Govitecan and Radiation Therapy

Nellie Nafissi, Nejina Rijal, Ritesh Parajuli, Aditya Mahadevan, Elaine Chiao
article en

Abstract

This case report documents the first case of orbital metastases successfully treated with radiation therapy and sacituzumab govitecan. As such, this case highlights the importance of sacituzumab govitecan as a potentially effective option for TNBC patients with CNS disease. Further studies and real-world data are needed to investigate the efficacy of combined radiotherapy and sacituzumab govitecan toward ocular metastases.

Cancer ReportsVol. 9(2)
University of California, Los Angeles (US), University of California, San Francisco (US), University of California, Irvine (US)
Good health and well-being
Openalex Percentile: Top 66%
Ocular Oncology and Treatments
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