Chronic hepatitis D in Austria: high burden of cirrhosis and portal hypertension, IL28B C/C as unfavorable factor, increased systemic inflammation in decompensation
This analysis of the Austrian CHD cohort before initiation of antiviral treatment showed a high burden of ACLD and portal hypertension, especially when compared to CHB patients. The IL28B C/C SNP was associated with a more severe liver disease in CHD.
Authors
- Elmar Aigner (ORCID: https://orcid.org/0000-0003-0310-0536)
- Mattias Mandorfer (ORCID: https://orcid.org/0000-0003-2330-0017)
- Livia Dorn
- Marlene Panzer (ORCID: https://orcid.org/0000-0003-1957-412X)
- Michael Gschwantler
- Caroline Schwarz (ORCID: https://orcid.org/0000-0001-7762-7483)
- Alexander R. Moschen (ORCID: https://orcid.org/0000-0003-3598-7848)
- Andreas Maieron
- Thomas Reiberger (ORCID: https://orcid.org/0000-0002-4590-3583)
- Albert Friedrich Stättermayer (ORCID: https://orcid.org/0000-0003-0737-4091)
- Michael Straßer (ORCID: https://orcid.org/0000-0002-0913-7949)
- Mathias Jachs (ORCID: https://orcid.org/0000-0003-2871-4147)
- Heinz Zoller (ORCID: https://orcid.org/0000-0003-1794-422X)
- DJ Bauer
- Silvia Reiter
- Michael Schwarz
- Michael Trauner
- Marlene Hintersteininger
Institutions
- Sigmund Freud Privatuniversität Wien (AT)
- Johannes Kepler University of Linz (AT)
- Innsbruck Medical University (AT)
- Universität Innsbruck (AT)
- Paracelsus Medical University (AT)
- Universitätsklinikum St. Pölten (AT)
- ERN GUARD-Heart (NL)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Wiener klinische Wochenschrift
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1007/s00508-026-02700-4
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Gilead Sciences
- Universität Wien
- Medizinische Universität Wien