OPRM1 gene polymorphism linked to anxiety in cancer-related pain patients: an observational study

Our study indicates that G allele carriers exhibit lower anxiety levels, suggesting a certain correlation between the OPRM1 gene polymorphism and anxiety in cancer pain patients. Furthermore, there is a need to pay increased attention to the psychological health of cancer pain patients with the AA genotype.

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Publication Details

Journal
Frontiers in Pain Research
Published
2026-02-05
DOI
https://doi.org/10.3389/fpain.2026.1666510
Primary Topic
Pain Management and Opioid Use
Type
article
Field-Weighted Citation Impact
0.00
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article

OPRM1 gene polymorphism linked to anxiety in cancer-related pain patients: an observational study

X Li, Lei Hu, Jianwen Mo, Zhuolun Xie et al.
Frontiers in Pain Research
Pain Management and Opioid Use
article

OPRM1 gene polymorphism linked to anxiety in cancer-related pain patients: an observational study

X Li, Lei Hu, Jianwen Mo, Zhuolun Xie, Xiaolin Xia, Min Chen
article en

Abstract

Our study indicates that G allele carriers exhibit lower anxiety levels, suggesting a certain correlation between the OPRM1 gene polymorphism and anxiety in cancer pain patients. Furthermore, there is a need to pay increased attention to the psychological health of cancer pain patients with the AA genotype.

Frontiers in Pain ResearchVol. 7
Yuncheng University (CN), Nanfang Hospital (CN), Southern Medical University (CN)
Openalex Percentile: Top 64%
Pain Management and Opioid Use
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