Conductive MXene/adECM hydrogel promotes skeletal muscle regeneration and innervation through Ca2+ influx modulation and neuromuscular junction formation
Together, these findings demonstrate that the incorporation of MXenes into adECM provides a promising strategy that integrates microenvironmental support with endogenous electrical cues to modulate calcium influx and promote NMJ formation, offering a new paradigm for the treatment of VML.
Authors
- Wanwen Dang
- Mengying Jin (ORCID: https://orcid.org/0000-0001-5727-5425)
- Yang An (ORCID: https://orcid.org/0000-0003-2887-516X)
- Hongxu Wu (ORCID: https://orcid.org/0009-0004-5797-1155)
- Ya Zhang (ORCID: https://orcid.org/0000-0003-0894-4922)
- Yonghuan Zhen
- Rigele Ao
- Meng Han
- Yuchen Zhou
- Wei Liang
Institutions
- Peking University (CN)
- Beijing Academy of Artificial Intelligence (CN)
- Peking University Third Hospital (CN)
- Beijing University of Chemical Technology (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1186/s12951-026-04077-y
- Citations
- 1
- Primary Topic
- MXene and MAX Phase Materials
- Type
- article
- Field-Weighted Citation Impact
- 16.08