Challenges in diagnosing cryptococcosis among HIV-infected patients in southern Mozambique and opportunities for intervention in contexts of limited resources: A pre-implementation study

Frequent stock-outs of rapid diagnostic tests and challenges associated with performing lumbar punctures are barriers to routine screening for cryptococcosis. In contrast, we have identified the universal availability of microscopes and health workers' recognition of the problem, as well as their willingness to collaborate, as potential facilitators to leverage for the successful reintroduction of India ink microscopy of urine samples as a low-cost laboratory test alternative.

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Publication Details

Journal
PLoS ONE
Published
2026-02-05
DOI
https://doi.org/10.1371/journal.pone.0340217
Primary Topic
Fungal Infections and Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Challenges in diagnosing cryptococcosis among HIV-infected patients in southern Mozambique and opportunities for intervention in contexts of limited resources: A pre-implementation study

Troy D. Moon, José Carlos Langa, Mohsin Sidat, Jahit Sacarlal
PLoS ONE
Fungal Infections and Studies
article

Challenges in diagnosing cryptococcosis among HIV-infected patients in southern Mozambique and opportunities for intervention in contexts of limited resources: A pre-implementation study

Troy D. Moon, José Carlos Langa, Mohsin Sidat, Jahit Sacarlal
article en

Abstract

Frequent stock-outs of rapid diagnostic tests and challenges associated with performing lumbar punctures are barriers to routine screening for cryptococcosis. In contrast, we have identified the universal availability of microscopes and health workers' recognition of the problem, as well as their willingness to collaborate, as potential facilitators to leverage for the successful reintroduction of India ink microscopy of urine samples as a low-cost laboratory test alternative.

PLoS ONEVol. 21(2)
Tulane University (US), Eduardo Mondlane University (MZ), Hospital for Tropical Diseases (VN)
Good health and well-being
Openalex Percentile: Top 65%
Fungal Infections and Studies
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