Natural inhibitors of PTP1B: Caffeic acid, cinnamic acid, and cinnamaldehyde as promising agents against triple-negative breast cancer
Both Caffeic acid and cinnamic acid had an inhibitory effect on the cell viability of the MDA-MB-231 cell line. MCF-7 studies showed that caffeic acid had an inhibitory effect on cells, but cinnamic acid had this effect only on MCF-7 cells. HB2 cells have shown reduced viability, which is significantly higher than that of MCF-7 cell lines.
Authors
- Magdalena Górska‐Ponikowska (ORCID: https://orcid.org/0000-0002-7366-8429)
- Giuseppe Vergilio (ORCID: https://orcid.org/0009-0002-8670-6356)
- F. Rappa
- Alicja Kuban-Jankowska
- Michał Suchecki
- Maria Denise Amico
- Joanna Herkt
Institutions
- Institute for Biomedical Research and Innovation (IT)
- Gdańsk Medical University (PL)
- University of Palermo (IT)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1016/j.biopha.2026.119006
- Citations
- 1
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article
- Field-Weighted Citation Impact
- 22.24