Efficacy and safety of Nefecon in IgA nephropathy: real world clinical practice

In routine clinical practice, Nefecon effectively reduces proteinuria and preserves renal function in IgAN, even in patients excluded from randomized trials. The combination with immunosuppressive therapy may provide additive benefit that requires further validation. These findings extend trial results to real-world settings and highlight Nefecon as a practical treatment option for high-risk IgAN patients.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-02-05
DOI
https://doi.org/10.3389/fimmu.2026.1761804
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
0.00

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article

Efficacy and safety of Nefecon in IgA nephropathy: real world clinical practice

Zihan Zhai, Zhibin Huang, Y H Guo, Qiuhong Li et al.
Frontiers in Immunology
Renal Diseases and Glomerulopathies
article

Efficacy and safety of Nefecon in IgA nephropathy: real world clinical practice

Zihan Zhai, Zhibin Huang, Y H Guo, Qiuhong Li, Lu Yu, Lin Tang, Rong Gou, Liuwei Wang, Yulin Wang
article en

Abstract

In routine clinical practice, Nefecon effectively reduces proteinuria and preserves renal function in IgAN, even in patients excluded from randomized trials. The combination with immunosuppressive therapy may provide additive benefit that requires further validation. These findings extend trial results to real-world settings and highlight Nefecon as a practical treatment option for high-risk IgAN patients.

Frontiers in ImmunologyVol. 17
First Affiliated Hospital of Zhengzhou University (CN)
Zhengzhou University, First Affiliated Hospital of Zhengzhou University
Openalex Percentile: Top 70%
Renal Diseases and Glomerulopathies
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