Time-dependent neurovascular unit dysfunction in ischemic stroke: mechanisms of neurovascular uncoupling and its clinical impact
NVU dysfunction underlies both acute injury amplification and chronic recovery failure after stroke. Biomarker-guided, phase-specific therapeutic strategies targeting inflammation, oxidative stress and BBB instability represent a promising framework for personalized stroke management.
Authors
- Mainak Sinha (ORCID: https://orcid.org/0000-0002-2286-0701)
- Gagan Anand (ORCID: https://orcid.org/0000-0001-7837-0114)
- Bandana Kumari
- Rijhul Lahariya
- Keyush Venket Subramanian
Institutions
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- International Journal of Neuroscience
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1080/00207454.2026.2627246
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00