The Association Between Placental Pathology in Fetuses with Fetal Growth Restriction and Maternal and Neonatal Outcomes Post-Delivery

Background and aims: Placental insufficiency causes many pregnancy complications, including fetal growth retardation (FGR), and may be related to placental pathology. This study investigated the relationship between the placental pathology of different FGR grades and pregnancy outcomes. Methods: In this prospective study, 67 patients diagnosed with FGR during pregnancy with different grades were included in the study. After birth, their final placental pathology was examined, and the relationship between final placental pathology and fetal and maternal outcomes was investigated. Data were analyzed by SPSS version 26. Results: A significant relationship was observed between accelerated villus maturation pathology and FGR grading, birth weight, postnatal placental weight, and neonatal outcome one month after birth. Accordingly, the cases with accelerated villous maturation had a higher death rate at the end of one month in their babies (P=0.02). Conclusion: Placental pathology is an applicable tool for predicting pregnancy and maternal and neonatal outcomes.