Mechanical Stretch Disrupts Calcium Dynamics and Redistributes Piezo1 in Human Astrocytes
This platform captures functional and molecular hallmarks of astrocyte injury and provides a human in vitro model for studying mechanobiological pathways linking TBI to neurodegenerative processes.
Authors
- John D. Finan (ORCID: https://orcid.org/0000-0003-4626-9702)
- Karmel W. Choi (ORCID: https://orcid.org/0000-0002-3914-2431)
- H Gao
- Kristen Brennand (ORCID: https://orcid.org/0000-0003-0993-5956)
- Carina Seah (ORCID: https://orcid.org/0000-0003-1604-1838)
- Akash Chakka
- Angela Mitevska
- Shahrzad Shiravi
- Xi Xiao (ORCID: https://orcid.org/0000-0003-1521-9542)
- Alexandra Yufa
- Meilin Fernandez Garcia
Institutions
- Yale University (US)
- University of Illinois Chicago (US)
- University of Chicago (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Annals of Biomedical Engineering
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1007/s10439-026-03995-0
- Primary Topic
- Erythrocyte Function and Pathophysiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00