Genetic association of miR-146a, miR-196a2, and miR-499 polymorphisms with hepatocellular carcinoma risk in an Eastern Chinese population

Our findings suggest that miR-196a2 rs11614913 and miR-499 rs3746444 polymorphisms are significantly associated with HCC susceptibility in the eastern Chinese population and may serve as potential genetic biomarkers for early risk assessment.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-06
DOI
https://doi.org/10.3389/fonc.2026.1707963
Primary Topic
MicroRNA in disease regulation
Type
article
Field-Weighted Citation Impact
0.00

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article

Genetic association of miR-146a, miR-196a2, and miR-499 polymorphisms with hepatocellular carcinoma risk in an Eastern Chinese population

Tao Xu, Qing You Pang, Lunjun Zhang, Xiaolin Ding et al.
Frontiers in Oncology
MicroRNA in disease regulation
article

Genetic association of miR-146a, miR-196a2, and miR-499 polymorphisms with hepatocellular carcinoma risk in an Eastern Chinese population

Tao Xu, Qing You Pang, Lunjun Zhang, Xiaolin Ding, Hongtao Wang
article en

Abstract

Our findings suggest that miR-196a2 rs11614913 and miR-499 rs3746444 polymorphisms are significantly associated with HCC susceptibility in the eastern Chinese population and may serve as potential genetic biomarkers for early risk assessment.

Frontiers in OncologyVol. 16
Anhui Medical University (CN), Second Affiliated Hospital of Anhui Medical University (CN), First Affiliated Hospital of Bengbu Medical College (CN)
Anhui Provincial Department of Education
Good health and well-being
Openalex Percentile: Top 67%
MicroRNA in disease regulation
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Genetic association of miR-146a, miR-196a2, and miR-499 polymorphisms with hepatocellular carcinoma risk in an Eastern Chinese population — Tao Xu, Qing You Pang, et al. · Frontiers in Oncology (2026) | TGRS Research Map | TGRS