Bioprocess Digital Twin as Training and Educational Tool

Digital twins are a key technology of industry 4.0 and are a powerful tool for operator training simulations (OTS). This work presents a digital twin for a bioprocess. Possible applications in higher education and corresponding learning objectives are presented and discussed. The digital twin is capable of simulating various upstream operation modes (e. g. batch, fed batch, chemostat) and also addresses the issue of automating those processes using sequential function charts (SFC). From a didactic point of view, digital twins have numerous advantages. Students can be introduced to complex issues in a vivid manner. Using a digital twin also reduces the fear of making errors or wrong decisions. Students can freely perform virtual experiments with different parameters and configurations, ultimately leading to a more confident operation of real processes.

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Publication Details

Journal
Universität Stuttgart - Journal of Technical Education
Published
2025-06-30
DOI
https://doi.org/10.48513/joted.v14i1.323
Primary Topic
Digital Transformation in Industry
Type
article
Field-Weighted Citation Impact
0.00
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article

Bioprocess Digital Twin as Training and Educational Tool

Richard Biener, Johannes Hofmann
Universität Stuttgart - Journal of Technical Education
Digital Transformation in Industry
article

Bioprocess Digital Twin as Training and Educational Tool

Richard Biener, Johannes Hofmann
article en

Abstract

Digital twins are a key technology of industry 4.0 and are a powerful tool for operator training simulations (OTS). This work presents a digital twin for a bioprocess. Possible applications in higher education and corresponding learning objectives are presented and discussed. The digital twin is capable of simulating various upstream operation modes (e. g. batch, fed batch, chemostat) and also addresses the issue of automating those processes using sequential function charts (SFC). From a didactic point of view, digital twins have numerous advantages. Students can be introduced to complex issues in a vivid manner. Using a digital twin also reduces the fear of making errors or wrong decisions. Students can freely perform virtual experiments with different parameters and configurations, ultimately leading to a more confident operation of real processes.

Universität Stuttgart - Journal of Technical Education
Esslingen University of Applied Sciences (DE)
Openalex Percentile: Top 27%
Digital Transformation in Industry
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Bioprocess Digital Twin as Training and Educational Tool — Richard Biener, Johannes Hofmann · Universität Stuttgart - Journal of Technical Education (2025) | TGRS Research Map | TGRS