Genomic Evolution of Influenza A Virus During the 2024–2025 Season, the Johns Hopkins Health System: Antigenic Drift Reduces Serum Neutralization
These findings demonstrate ongoing antigenic drift and the presence of antiviral resistance-associated mutations during the 2024-2025 influenza season, underscoring the need for continued genomic surveillance to guide vaccine and antiviral strategies.
Authors
- Elgin Akin (ORCID: https://orcid.org/0000-0001-8824-8809)
- Yee Vue
- Julie M. Norton (ORCID: https://orcid.org/0000-0001-6270-5557)
- Andrew Pekosz (ORCID: https://orcid.org/0000-0003-3248-1761)
- David A. Villafuerte
- Eili Y. Klein
- Matthew Pinsley
- Katherine Z J Fenstermacher
- Anne P Werner
- C Paul Morris
- Richard E Rothman
- Ting Xuan Zhuang
- Omar Abdullah
- Amary Fall
Institutions
- National Institutes of Health (US)
- Center for Disease Dynamics, Economics & Policy (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- Johns Hopkins Bayview Medical Center (US)
- National Institute of Allergy and Infectious Diseases (US)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1093/infdis/jiag069
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00