Effect of Rituximab on Neurofilament Levels in <scp>CIDP</scp> : Results From the <scp>CIDPRIT</scp> Randomized Trial

The analysis did not demonstrate biomarker-based evidence of rituximab efficacy in CIDP. However, observed trends suggest a possible biological effect in reducing axonal injury in a subset of patients. Further studies are needed to clarify the role of sNfL in treatment monitoring and patient stratification.

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Publication Details

Journal
Journal of the Peripheral Nervous System
Published
2026-02-06
DOI
https://doi.org/10.1111/jns.70107
Primary Topic
Skin and Cellular Biology Research
Type
article
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article

Effect of Rituximab on Neurofilament Levels in CIDP : Results From the CIDPRIT Randomized Trial

L. Querol, Chiara Gallo, Elisa Bianchi, Luca Gentile et al.
Journal of the Peripheral Nervous System
Skin and Cellular Biology Research
article

Effect of Rituximab on Neurofilament Levels in CIDP : Results From the CIDPRIT Randomized Trial

L. Querol, Chiara Gallo, Elisa Bianchi, Luca Gentile, Yuri Falzone, Luana Benedetti, Erdita Peci, Camilla Strano, Giuseppe Liberatore, Claudia Cutellè, Fiore Manganelli, Francesco Germano, Anna Mazzeo, Roger Collet-Vidiella, Eduardo Nobile-Orazio, Dario Cocito, Eleonora Dalla Bella
article en

Abstract

The analysis did not demonstrate biomarker-based evidence of rituximab efficacy in CIDP. However, observed trends suggest a possible biological effect in reducing axonal injury in a subset of patients. Further studies are needed to clarify the role of sNfL in treatment monitoring and patient stratification.

Journal of the Peripheral Nervous SystemVol. 31(1)
University of Messina (IT), Humanitas University (IT), Vita-Salute San Raffaele University (IT), University of Milan (IT), Mario Negri Institute for Pharmacological Research (IT), Hospital de Sant Pau (ES), San Raffaele University of Rome (IT), Federico II University Hospital (IT), Molecular Cardiology and Neuromuscular Institute (US), Ospedale Policlinico San Martino (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), IRCCS Humanitas Research Hospital (IT), Fondazione IRCCS Istituto Neurologico Carlo Besta (IT), University of Turin (IT), University of Naples Federico II (IT), University of Genoa (IT)
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Openalex Percentile: Top 68%
Skin and Cellular Biology Research
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Effect of Rituximab on Neurofilament Levels in <scp>CIDP</scp> : Results From the <scp>CIDPRIT</scp> Randomized Trial — L. Querol, Chiara Gallo, et al. · Journal of the Peripheral Nervous System (2026) | TGRS Research Map | TGRS