Urinary CXCL-9 outperforms TNF-α for non-invasive diagnosis of immune checkpoint inhibitor–associated acute interstitial nephritis

Increased urinary CXCL-9 was superior to TNF-α as a biomarker for the non-invasive diagnosis of ICI-AIN, even after prior corticosteroid exposure, highlighting its promise as clinical diagnostic tool.

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Publication Details

Journal
Nephrology Dialysis Transplantation
Published
2026-01-28
DOI
https://doi.org/10.1093/ndt/gfag016
Citations
1
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
24.20
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Urinary CXCL-9 outperforms TNF-α for non-invasive diagnosis of immune checkpoint inhibitor–associated acute interstitial nephritis

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article

Urinary CXCL-9 outperforms TNF-α for non-invasive diagnosis of immune checkpoint inhibitor–associated acute interstitial nephritis

Gurparneet Kaur Sohi, Coraima Claudia Nava Chavez, Sheila Rubio Bermejo, Lisa A. Kottschade, María José Soler, S. Markovic, Callen D. Giesen, Omar Al Refai, Nelson Leung, John C Lieske, Victor Cuenca Narvaez, Sandra M Herrmann
article en
1 citations

Abstract

Increased urinary CXCL-9 was superior to TNF-α as a biomarker for the non-invasive diagnosis of ICI-AIN, even after prior corticosteroid exposure, highlighting its promise as clinical diagnostic tool.

Nephrology Dialysis Transplantation
Hebron University (PS), Mayo Clinic (US), Mayo Clinic in Arizona (US), Mayo Clinic in Florida (US)
Good health and well-being
Openalex Percentile: Top 1%
Cancer Immunotherapy and Biomarkers
24.20
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