Prevention of surgical site infections in lower limb fracture fixation and elective arthroplasty: a systematic review and meta-analysis of decolonization and skin antisepsis strategies

Nasal and skin decolonization protocols seem to reduce the incidence of SSIs in elective hip and knee arthroplasty. Thereby, skin, nasal and combined decolonization strategies may be used. However, current evidence in fracture surgery remains insufficient and inconsistent. High-quality randomized trials are urgently needed to evaluate decolonization efficacy in lower extremity trauma surgery.

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Publication Details

Journal
Antimicrobial Resistance and Infection Control
Published
2026-02-06
DOI
https://doi.org/10.1186/s13756-026-01713-y
Primary Topic
Surgical site infection prevention
Type
article
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article

Prevention of surgical site infections in lower limb fracture fixation and elective arthroplasty: a systematic review and meta-analysis of decolonization and skin antisepsis strategies

Christina Pempe, Christoph Hellmund, Dirk Hasenclever, Iris Freya Chaberny et al.
Antimicrobial Resistance and Infection Control
Surgical site infection prevention
article

Prevention of surgical site infections in lower limb fracture fixation and elective arthroplasty: a systematic review and meta-analysis of decolonization and skin antisepsis strategies

Christina Pempe, Christoph Hellmund, Dirk Hasenclever, Iris Freya Chaberny, Babak Moradi, Andreas Roth, Christian Kleber
article en

Abstract

Nasal and skin decolonization protocols seem to reduce the incidence of SSIs in elective hip and knee arthroplasty. Thereby, skin, nasal and combined decolonization strategies may be used. However, current evidence in fracture surgery remains insufficient and inconsistent. High-quality randomized trials are urgently needed to evaluate decolonization efficacy in lower extremity trauma surgery.

Antimicrobial Resistance and Infection ControlVol. 15(1)
Christian-Albrechts-Universität zu Kiel (DE), University Hospital Schleswig-Holstein (DE), University Hospital Leipzig (DE), Leipzig University (DE), University of Lübeck (DE)
Good health and well-being
Openalex Percentile: Top 66%
Surgical site infection prevention
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