Genetic liability to addiction underlies comorbid bipolar and substance use disorders
By dissecting the genetic liability to SUD and SU and investigating their relationship with BIP we find a genetic link driven by substance dependence but not substance use more broadly.
Authors
- Ibrahim A. Akkouh
- Pravesh Parekh (ORCID: https://orcid.org/0000-0002-1930-1167)
- Ida E. Soenderby
- Espen Hagen
- Nadine Parker (ORCID: https://orcid.org/0000-0002-8369-0152)
- Lars Ystaas
- Oleksandr Frei
- Kevin S. O'Connell
- Viktoria Birkenaes
- Alexey Shadrin
- Elise Koch
- Ole A. Andreassen
Institutions
- Oslo University Hospital (NO)
- J. Craig Venter Institute (US)
- University of Oslo (NO)
- Precision for Medicine (United States) (US)
- Diakonhjemmet Hospital (NO)
Publication Details
- Journal
- medRxiv
- Published
- 2026-02-05
- DOI
- https://doi.org/10.64898/2026.02.04.26345483
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Stiftelsen Kristian Gerhard Jebsen
- Trond Mohn stiftelse
- European Commission
- Helse- og Omsorgsdepartementet
- Novo Nordisk
- Universitetet i Bergen
- Universitetet i Oslo
- Norges Forskningsråd
- National Institutes of Health
- Norwegian Institute of Public Health