Breast arterial calcifications on mammography and risk of stroke: a systematic review and meta-analysis

BAC detected on screening mammography is independently associated with an increased risk of stroke, even after accounting for traditional risk factors. These findings support BAC as a promising, underutilized imaging biomarker of cerebrovascular risk in women and highlight the need for standardized reporting and prospective validation.

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Publication Details

Journal
Frontiers in Neurology
Published
2026-02-05
DOI
https://doi.org/10.3389/fneur.2026.1716747
Primary Topic
Digital Radiography and Breast Imaging
Type
article
Field-Weighted Citation Impact
0.00
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Breast arterial calcifications on mammography and risk of stroke: a systematic review and meta-analysis

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Breast arterial calcifications on mammography and risk of stroke: a systematic review and meta-analysis

Ramanathan Kadirvel, Amy Lynn Conners, Adam Andrew Dmytriw, Seyed Behnam Jazayeri, Abdolkarim Haji Ghadery, Pedram Pakzamir, Muhayman Sadiq, Mohamed Ahmed Ali, Mohammad Reza Fattahi, Rachana R. Borkar, Sherief Ghozy, David F. Kallmes
article en

Abstract

BAC detected on screening mammography is independently associated with an increased risk of stroke, even after accounting for traditional risk factors. These findings support BAC as a promising, underutilized imaging biomarker of cerebrovascular risk in women and highlight the need for standardized reporting and prospective validation.

Frontiers in NeurologyVol. 17
Islamic Azad University, Tehran (IR), Brigham and Women's Hospital (US), Neurosciences Institute (US), South Valley University (EG), WinnMed (US), Yale University (US), University of Oxford (GB), Bioanalytica (Switzerland) (CH), Mayo Clinic in Arizona (US), The University of Texas Health Science Center (US), Utenos kolegija Higher Education Institution (LT), Shahid Beheshti University of Medical Sciences (IR), Tehran University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 68%
Digital Radiography and Breast Imaging
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