Serial insulin and C-peptide concentrations following high-dose insulin for the treatment of drug poisoning: a consecutive case series
This study identified a shorter insulin elimination half-life after discontinuing high-dose insulin than previously reported. Measuring serial insulin and C-peptide concentrations may guide clinical decisions, including dextrose weaning and confirm resolution of hyperinsulinaemia.
Authors
- Lori Coulson
- Úna Nic Ionmhain (ORCID: https://orcid.org/0000-0003-4818-4980)
- Darren M. Roberts
Institutions
- Royal Prince Alfred Hospital (AU)
- Liverpool Hospital (AU)
- Royal Hobart Hospital (AU)
- UNSW Sydney (AU)
- Sydney Children’s Hospitals Network (AU)
Publication Details
- Journal
- Clinical Toxicology
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1080/15563650.2026.2613033
- Primary Topic
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Type
- article
- Field-Weighted Citation Impact
- 0.00