Exercise Training and Progression of Chronic Kidney Disease: The GFR-Exercise (GFR-Ex) Randomized Controlled Feasibility Study

In people with progressive CKD, a 12-month exercise training program was safe and feasible. Exercise tended to attenuate GFR decline, and eGFR agreed well with mGFR. Progression to a definitive trial is warranted, provided modifications are made, including providing patient support and selection of eGFR as the primary outcome.

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Publication Details

Journal
American Journal of Nephrology
Published
2026-02-05
DOI
https://doi.org/10.1159/000549971
Primary Topic
Chronic Kidney Disease and Diabetes
Type
article
Field-Weighted Citation Impact
0.00
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article

Exercise Training and Progression of Chronic Kidney Disease: The GFR-Exercise (GFR-Ex) Randomized Controlled Feasibility Study

Juliet Briggs, Sharlene A. Greenwood, Jamie Macdonald, Abdulfattah Alejmi et al.
American Journal of Nephrology
Chronic Kidney Disease and Diabetes
article

Exercise Training and Progression of Chronic Kidney Disease: The GFR-Exercise (GFR-Ex) Randomized Controlled Feasibility Study

Juliet Briggs, Sharlene A. Greenwood, Jamie Macdonald, Abdulfattah Alejmi, Mark David Davies
article en

Abstract

In people with progressive CKD, a 12-month exercise training program was safe and feasible. Exercise tended to attenuate GFR decline, and eGFR agreed well with mGFR. Progression to a definitive trial is warranted, provided modifications are made, including providing patient support and selection of eGFR as the primary outcome.

American Journal of Nephrology
Betsi Cadwaladr University Health Board (GB), Bangor University (GB), King's College London (GB), King's College Hospital (GB)
Openalex Percentile: Top 70%
Chronic Kidney Disease and Diabetes
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