Characterization of drug resistance mutations in people living with HIV with low-level viremia on antiretroviral therapy in Chongqing, China

This study reveals a considerable prevalence of drug mutations (DRMs), predominantly against NNRTIs, among ART-experienced PLWH with LLV in Chongqing. The combined RNA/DNA genotyping strategy significantly enhanced DRM detection sensitivity in this low viral load cohort, underscoring its value for resistance surveillance and guiding clinical management in resource-limited settings.