Extracompartmental Two-Injection Technique for Treating De Quervain Tenosynovitis

In this study, we prospectively analyzed patients diagnosed with and treated for De Quervain tenosynovitis (DQT) to evaluate the efficacy of a novel extracompartmental two-injection technique. Fifteen patients completed a Visual Analog Scale for pain, grip strength testing, and physical examination before receiving injections. After four weeks, these same measurements were repeated and compared to baseline. Statistical analysis was conducted using two-tailed t-tests to compare symptoms before and four weeks after treatment, pain associated with each injection, and grip strength before and four weeks after treatment. Results suggest that the extracompartmental two-injection technique led to significant symptom improvement and absent physical exam findings in 100% of patients, complete symptom resolution in 73% of patients, and improved grip strength in 93% of patients with DQT. We describe this reproducible technique to help providers and patients avoid the pain and risks associated with intracompartmental steroid injection while still achieving short-term outcomes comparable to those reported with other injection techniques.

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Publication Details

Journal
Cureus
Published
2026-02-04
DOI
https://doi.org/10.7759/cureus.102956
Primary Topic
Orthopedic Surgery and Rehabilitation
Type
article
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article

Extracompartmental Two-Injection Technique for Treating De Quervain Tenosynovitis

Jeffrey A. Marchessault, Tyler S Iodence, William F McCormick
Cureus
Orthopedic Surgery and Rehabilitation
article

Extracompartmental Two-Injection Technique for Treating De Quervain Tenosynovitis

Jeffrey A. Marchessault, Tyler S Iodence, William F McCormick
article en

Abstract

In this study, we prospectively analyzed patients diagnosed with and treated for De Quervain tenosynovitis (DQT) to evaluate the efficacy of a novel extracompartmental two-injection technique. Fifteen patients completed a Visual Analog Scale for pain, grip strength testing, and physical examination before receiving injections. After four weeks, these same measurements were repeated and compared to baseline. Statistical analysis was conducted using two-tailed t-tests to compare symptoms before and four weeks after treatment, pain associated with each injection, and grip strength before and four weeks after treatment. Results suggest that the extracompartmental two-injection technique led to significant symptom improvement and absent physical exam findings in 100% of patients, complete symptom resolution in 73% of patients, and improved grip strength in 93% of patients with DQT. We describe this reproducible technique to help providers and patients avoid the pain and risks associated with intracompartmental steroid injection while still achieving short-term outcomes comparable to those reported with other injection techniques.

CureusVol. 18(2)
East Tennessee State University (US), Watauga Medical Center (US)
Good health and well-being
Openalex Percentile: Top 66%
Orthopedic Surgery and Rehabilitation
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Extracompartmental Two-Injection Technique for Treating De Quervain Tenosynovitis — Jeffrey A. Marchessault, Tyler S Iodence, et al. · Cureus (2026) | TGRS Research Map | TGRS