Multicenter real-world data on immunotherapy for R/M HNSCC from China: comprehensive analysis of efficacy and survival differences across diverse clinical backgrounds, and identification of predictive peripheral blood biomarkers
This study focused on evaluating immunotherapy efficacy and survival differences in R/M HNSCC patients across various clinical background. Dynamic PBMs correlated closely with immunotherapy response and survival prognosis. These findings expanded treatment options and supported personalized decisions. R/M HNSCC, Immunotherapy, Real-world study, Efficacy and survival differences, Predictive markers.
Authors
- Shasha Pu
- Jian Zang
- M. Shi
- Dongbo Jiang (ORCID: https://orcid.org/0000-0002-2675-5634)
- Lina Zhao
- J Liu
- Changhao Liu (ORCID: https://orcid.org/0000-0002-3050-4803)
- Siyu Wang (ORCID: https://orcid.org/0009-0002-4064-6984)
- Feifan Sun
- Zhongwei Wang
- Bingxin Hou
- Haichuan Su
- Xuejiao Song
Institutions
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
- Tang Du Hospital (CN)
- Xijing Hospital (CN)
- Command Hospital (IN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-04
- DOI
- https://doi.org/10.3389/fimmu.2026.1720838
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00