Analysis of metabolic status and risk factors of small for gestational age children with catch-up growth in East China
(1) IGF-1 SDS was significantly positively correlated with fasting INS (FINS) and HOMA-IR, and exerted a significant positive effect on fasting BG. If IGF-1 levels in CUG-SGA infants remain persistently high, careful monitoring of changes in glucose metabolism is warranted. (2) CUG-SGA patients had higher LEP resistance compared to NCUG-SGA patients, potentially contributing to future metabolic issues. (3) Elevated ALT and GGT levels in SGA patients may warrant close monitoring of glucose metabolism, particularly in CUG-SGA patients.
Authors
- Meiling Yan (ORCID: https://orcid.org/0000-0001-7652-129X)
- Kan Ye (ORCID: https://orcid.org/0000-0001-7109-2334)
- yanchun shan
- Ning Li (ORCID: https://orcid.org/0000-0003-4533-1535)
- Xi Zhang (ORCID: https://orcid.org/0000-0002-4638-3997)
- Junqi Wang (ORCID: https://orcid.org/0000-0002-4774-0263)
- Qiong Tang (ORCID: https://orcid.org/0000-0002-1276-6439)
- Meizhu Xue
- Wei Cao (ORCID: https://orcid.org/0000-0001-5628-7918)
- Huayan Hu
- Yanghua Dan
- Li Zhou
- Xianglan Wen
- Wendi Zhou
- Zhiya Dong
- Hongmei Dai
- Ruifang Wang
- Yanan Liu
- Hongbo Wu
Institutions
- Qingdao University (CN)
- Central South University (CN)
- Ruijin Hospital (CN)
- Bozhou People's Hospital (CN)
- Affiliated Hospital of Qingdao University (CN)
- Xiangyang Central Hospital (CN)
- Jiangxi Pingxiang People's Hospital (CN)
- Changshu No.1 People's Hospital (CN)
- Zhuzhou Central Hospital (CN)
- Jiujiang Maternal and Child Care Centres (CN)
- Shandong Maternal and Child Health Hospital (CN)
- Third Xiangya Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- BMC Pediatrics
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1186/s12887-025-05868-2
- Primary Topic
- Growth Hormone and Insulin-like Growth Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00