Glucose and Lactate Concentrations in Plasma, Cerebrospinal Fluid, and Brain Parenchyma Following Aneurysmal Subarachnoid Hemorrhage: A Cross-compartmental Correlation Study
In severe aSAH, glucose and lactate levels in blood and CSF reflect cerebral values in a compartment- and metabolite-specific manner, but with high variability influenced by clinical conditions. These findings suggest that blood and CSF provide only limited information about cerebral metabolism, highlighting the complementary value of cerebral microdialysis for individualized, brain-targeted monitoring.
Authors
- Johannes Herta (ORCID: https://orcid.org/0000-0002-2962-6205)
- Robin Ristl (ORCID: https://orcid.org/0000-0002-4163-9236)
- Miriam M. Moser (ORCID: https://orcid.org/0009-0007-5317-1881)
- Arthur Hosmann (ORCID: https://orcid.org/0000-0001-7396-4239)
- Walter Plöchl (ORCID: https://orcid.org/0000-0003-3761-1326)
- Karl Rössler (ORCID: https://orcid.org/0000-0002-9249-8082)
- Lena Weyer
- Andrea Reinprecht
- Niko Schmaling
Institutions
- Statistics Austria (AT)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Neurocritical Care
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1007/s12028-025-02442-7
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universität Wien
- Medizinische Universität Wien