Toxoplasma gondii assembles extracellular vesicles with conserved lipid profiles across host cell types

These findings indicate that T. gondii produces vesicles with conserved and distinctive lipid compositions that differ from those of the host cell. This selective lipid core hints at key functions in parasite, host communication, immune modulation, nutrient acquisition, and other vesicle-cell interactions. Our work advances the molecular understanding of TgEVs and establishes a foundation for future studies into how lipid-mediated signalling contributes to the complex dynamics of T. gondii infections in different cellular environments.