Cigarette smoking and SARS-CoV-2 infection: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study

We did not find robust evidence of causal associations between smoking and SARS-CoV-2 infection. Our investigation of potential violations to MR assumptions highlights the limitations of this approach to examine infection risk associated with smoking.

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Publication Details

Journal
BMC Infectious Diseases
Published
2026-02-04
DOI
https://doi.org/10.1186/s12879-026-12750-8
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00

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article

Cigarette smoking and SARS-CoV-2 infection: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study

Ida Henriette Caspersen, Ahmed Nabil Shaaban, M. R. Galanti, Per Magnus et al.
BMC Infectious Diseases
Genetic Associations and Epidemiology
article

Cigarette smoking and SARS-CoV-2 infection: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study

Ida Henriette Caspersen, Ahmed Nabil Shaaban, M. R. Galanti, Per Magnus, Álvaro Hernáez, Maria Christine Magnus, Sakari Karvonen, Sebastián Peña
article en

Abstract

We did not find robust evidence of causal associations between smoking and SARS-CoV-2 infection. Our investigation of potential violations to MR assumptions highlights the limitations of this approach to examine infection risk associated with smoking.

BMC Infectious DiseasesVol. 26(1)
Norwegian Institute of Public Health (NO), Instituto de Salud Carlos III (ES), Karolinska Institutet (SE), Finnish Institute for Health and Welfare (FI), Centro de Investigación en Red en Enfermedades Cardiovasculares (ES), Centre for Palaeogenetics (SE), Universitat Ramon Llull (ES)
Helse- og Omsorgsdepartementet
Good health and well-being
Openalex Percentile: Top 63%
Genetic Associations and Epidemiology
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