Current evidence on septic shock in patients with cirrhosis

Septic shock in patients with cirrhosis presents unique diagnostic and therapeutic challenges due to underlying hemodynamic changes and immune dysfunction. Conventional approaches to sepsis management may be insufficient or unreliable in this population, necessitating tailored strategies for fluid resuscitation and vasopressor use. High-quality evidence remains limited, and many current practices are based on extrapolation from the general population. Continued research is essential to develop targeted interventions and improve outcomes for this particularly vulnerable group.

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Publication Details

Journal
Current Opinion in Critical Care
Published
2026-02-04
DOI
https://doi.org/10.1097/mcc.0000000000001372
Primary Topic
Trauma, Hemostasis, Coagulopathy, Resuscitation
Type
article
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article

Current evidence on septic shock in patients with cirrhosis

Laura Piccolo Serafim, Alice Gallo de Moraes
Current Opinion in Critical Care
Trauma, Hemostasis, Coagulopathy, Resuscitation
article

Current evidence on septic shock in patients with cirrhosis

Laura Piccolo Serafim, Alice Gallo de Moraes
article en

Abstract

Septic shock in patients with cirrhosis presents unique diagnostic and therapeutic challenges due to underlying hemodynamic changes and immune dysfunction. Conventional approaches to sepsis management may be insufficient or unreliable in this population, necessitating tailored strategies for fluid resuscitation and vasopressor use. High-quality evidence remains limited, and many current practices are based on extrapolation from the general population. Continued research is essential to develop targeted interventions and improve outcomes for this particularly vulnerable group.

Current Opinion in Critical CareVol. 32(2)
Mayo Clinic (US), Mayo Clinic in Arizona (US), Mayo Clinic in Florida (US)
No poverty
Openalex Percentile: Top 66%
Trauma, Hemostasis, Coagulopathy, Resuscitation
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