Correlation of serum CTRP9 and CTRP15 levels with HOMA-IR and HOMA-B in metabolic syndrome patients with and without coronary artery disease

In this study, decreased insulin secretion was found to correlate with increased CTRP15 levels in patients with metabolic syndrome and coronary artery disease. This finding suggests the potential role of CTRP15 in the pathophysiology of beta cell dysfunction possibly reflecting either a state of CTRP15 resistance or a compensatory response to impaired insulin secretion.

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Publication Details

Journal
Pakistan Journal of Medical Sciences
Published
2026-01-26
DOI
https://doi.org/10.12669/pjms.42.2.12826
Primary Topic
Adipokines, Inflammation, and Metabolic Diseases
Type
article
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article

Correlation of serum CTRP9 and CTRP15 levels with HOMA-IR and HOMA-B in metabolic syndrome patients with and without coronary artery disease

Saba Khaliq, Fareena Ahmad, Hafiz Abdul Rehman Tariq, Uzma Zafar
Pakistan Journal of Medical Sciences
Adipokines, Inflammation, and Metabolic Diseases
article

Correlation of serum CTRP9 and CTRP15 levels with HOMA-IR and HOMA-B in metabolic syndrome patients with and without coronary artery disease

Saba Khaliq, Fareena Ahmad, Hafiz Abdul Rehman Tariq, Uzma Zafar
article en

Abstract

In this study, decreased insulin secretion was found to correlate with increased CTRP15 levels in patients with metabolic syndrome and coronary artery disease. This finding suggests the potential role of CTRP15 in the pathophysiology of beta cell dysfunction possibly reflecting either a state of CTRP15 resistance or a compensatory response to impaired insulin secretion.

Pakistan Journal of Medical SciencesVol. 42(2)
University of Health Sciences Lahore (PK), Institute of Public Health Bengaluru (IN)
Good health and well-being
Openalex Percentile: Top 65%
Adipokines, Inflammation, and Metabolic Diseases
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