Shared genetic architecture of psychiatric disorders and ocular diseases: Evidence from genome-wide analyses
This genome-wide study reveals genetic links between psychiatric and ocular diseases and provides evidence for bidirectional causality in selected phenotypes. Metabolism-inflammation-related pathways may contribute to comorbidity along the eye-brain axis, offering leads for future mechanistic validation.
Authors
- Cong Zhou
- Weijian Han
- Ting-ting Wang
- Jun-jie Luan
- Ping Sun
- Zhao-yang Zhang
- Xiao-jia Ma
- Xiang-wen Wang
- Huan-xi Liu
Institutions
- Qingdao University (CN)
- Qingdao Mental Health Center (CN)
- Affiliated Hospital of Qingdao University (CN)
- Jining Medical University (CN)
Publication Details
- Journal
- IBRO Neuroscience Reports
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1016/j.ibneur.2026.02.003
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00